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For more than ten years there have been regular reports, albeit anecdotal, of serious adverse
reactions by lrish Water Spanels to the commonly prescribed POTENTIATED SULPHONAMIDE group of antibiotics.
This
type of antibiotic proved to be both effective and economic in disease management following the Second World War. SULPHAMETHO)GZOLE
and TRIMETHOPRTM are used in combination for their synergistic activity and known by the generic term CO-TRIMOAXZOLE or CO-TRlM.
Co-trimoxazole was commonly prescribed by General Practitioners until the Autumn of 1994 when it waswlthdrawn
for human use, except in exceptional circumstances. This drug does, however, continue to be a popular choice in veterinary
medicine.
It is therefore advisable for all owners of the breed to alert their Veterlnary Practices and
Boarding Kennels to the risks involved. The breed would appear to have lost several animals, world wide, through the side
effects of Potentiated Sulphonamides, and many more dogs have been rendered seriously ill until treatment was withdrawn or
altered. The following brand names in addition to the generic CO-TRIMOXAZOLE, should be avoided or treated with caution when
prescriblng for lrish Water Spaniels:
TRIBRISSEN
DELVOPRIM
DUPHATRII\,4
NORODINE
TRIMACARE
CHANOPRIM
TRIMEDOXINE
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